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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
Q13185
USC-OGP 2-DE database
:
Q13185
Q13185
General information about the entry
View entry in simple text format
Entry name
CBX3_HUMAN
Primary accession number
Q13185
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Chromobox protein homolog 3; AltName: Full=HECH; AltName: Full=Heterochromatin protein 1 homolog gamma; Short=HP1 gamma; AltName: Full=Modifier 2 protein;.
Gene name
Name=CBX3
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1306
:
pI=5.02; Mw=22379
Cross-references
UniProtKB/Swiss-Prot
Q13185; CBX3_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
CBX3_HUMAN
Primary accession number
Q13185
Secondary accession number(s)
Q96CD7 Q99409 Q9BVS3 Q9P0Z6
Sequence was last modified on
October 17, 2006 (version 4)
Annotations were last modified on
March 15, 2017 (version 183)
Name and origin of the protein
Description
RecName: Full=Chromobox protein homolog 3; AltName: Full=HECH; AltName: Full=Heterochromatin protein 1 homolog gamma; Short=HP1 gamma; AltName: Full=Modifier 2 protein;
Gene name
Name=CBX3
Encoded on
Name=CBX3
Keywords
3D-structure
;
Acetylation
;
Biological rhythms
;
Chromatin regulator
;
Complete proteome
;
Direct protein sequencing
;
Isopeptide bond
;
Nucleus
;
Phosphoprotein
;
Reference proteome
;
Repeat
;
Repressor
;
Transcription
;
Transcription regulation
;
Ubl conjugation
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
U26312; AAB48101.1
; -; mRNA
EMBL
AB030905; BAA83340.1
; -; mRNA
EMBL
AF136630; AAF62370.1
; -; mRNA
EMBL
BC000954; AAH00954.1
; -; mRNA
EMBL
BC014380; AAH14380.1
; -; mRNA
CCDS
CCDS5398.1; -
; .
RefSeq
NP_009207.2; NM_007276.4
; .
RefSeq
NP_057671.2; NM_016587.3
; .
RefSeq
XP_005249668.1; XM_005249611.3
; .
UniGene
Hs.381189; -
; .
PDB
2L11; NMR
; -; A=29-81
PDB
3DM1; X-ray
; 2.40 A; A/C/E/G=29-86
PDB
3KUP; X-ray
; 1.77 A; A/B/C/D=110-173
PDB
3TZD; X-ray
; 1.81 A; A=29-81
PDB
5T1I; X-ray
; 1.60 A; A/B=110-176
PDBsum
2L11; -
; .
PDBsum
3DM1; -
; .
PDBsum
3KUP; -
; .
PDBsum
3TZD; -
; .
PDBsum
5T1I; -
; .
ProteinModelPortal
Q13185; -
; .
SMR
Q13185; -
; .
BioGrid
116463; 108
; .
DIP
DIP-5985N; -
; .
IntAct
Q13185; 108
; .
MINT
MINT-5002782; -
; .
STRING
9606.ENSP00000336687; -
; .
iPTMnet
Q13185; -
; .
PhosphoSitePlus
Q13185; -
; .
SwissPalm
Q13185; -
; .
BioMuta
CBX3; -
; .
DMDM
116241284; -
; .
SWISS-2DPAGE
Q13185; -
; .
EPD
Q13185; -
; .
MaxQB
Q13185; -
; .
PaxDb
Q13185; -
; .
PeptideAtlas
Q13185; -
; .
PRIDE
Q13185; -
; .
TopDownProteomics
Q13185; -
; .
DNASU
11335; -
; .
Ensembl
ENST00000337620; ENSP00000336687
; ENSG00000122565; .
Ensembl
ENST00000396386; ENSP00000379670
; ENSG00000122565; .
GeneID
11335; -
; .
KEGG
hsa:11335; -
; .
UCSC
uc003sxt.4; human
; .
CTD
11335; -
; .
DisGeNET
11335; -
; .
GeneCards
CBX3; -
; .
HGNC
HGNC:1553; CBX3
; .
HPA
CAB001973; -
; .
HPA
HPA004902; -
; .
MIM
604477; gene
; .
neXtProt
NX_Q13185; -
; .
OpenTargets
ENSG00000122565; -
; .
PharmGKB
PA26128; -
; .
eggNOG
KOG1911; Eukaryota
; .
eggNOG
ENOG4111JKD; LUCA
; .
GeneTree
ENSGT00510000046310; -
; .
HOGENOM
HOG000220852; -
; .
HOVERGEN
HBG000400; -
; .
InParanoid
Q13185; -
; .
KO
K11586; -
; .
OMA
RESADKP; -
; .
OrthoDB
EOG091G0RBS; -
; .
PhylomeDB
Q13185; -
; .
TreeFam
TF350503; -
; .
Reactome
R-HSA-427389; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
; .
Reactome
R-HSA-73777; RNA Polymerase I Chain Elongation
; .
SIGNOR
Q13185; -
; .
ChiTaRS
CBX3; human
; .
EvolutionaryTrace
Q13185; -
; .
GeneWiki
CBX3; -
; .
GenomeRNAi
11335; -
; .
PRO
PR:Q13185; -
; .
Proteomes
UP000005640; Chromosome 7
; .
Bgee
ENSG00000122565; -
; .
CleanEx
HS_CBX3; -
; .
ExpressionAtlas
Q13185; baseline and differential
; .
Genevisible
Q13185; HS
; .
GO
GO:0000785; C:chromatin
; IDA:UniProtKB; .
GO
GO:0000775; C:chromosome
; centromeric region; IDA:CACAO
GO
GO:0000779; C:condensed chromosome
; centromeric region; ISS:UniProtKB
GO
GO:0000784; C:nuclear chromosome
; telomeric region; IDA:BHF-UCL
GO
GO:0005635; C:nuclear envelope
; ISS:UniProtKB; .
GO
GO:0005719; C:nuclear euchromatin
; IDA:UniProtKB; .
GO
GO:0005720; C:nuclear heterochromatin
; IDA:UniProtKB; .
GO
GO:0005637; C:nuclear inner membrane
; NAS:UniProtKB; .
GO
GO:0031618; C:nuclear pericentric heterochromatin
; ISS:UniProtKB; .
GO
GO:0005634; C:nucleus
; IDA:UniProtKB; .
GO
GO:0035985; C:senescence-associated heterochromatin focus
; IEA:Ensembl; .
GO
GO:0005819; C:spindle
; IDA:UniProtKB; .
GO
GO:0019899; F:enzyme binding
; IPI:UniProtKB; .
GO
GO:1990226; F:histone methyltransferase binding
; IPI:BHF-UCL; .
GO
GO:0042802; F:identical protein binding
; IPI:IntAct; .
GO
GO:0019904; F:protein domain specific binding
; IPI:UniProtKB; .
GO
GO:0071549; P:cellular response to dexamethasone stimulus
; IEA:Ensembl; .
GO
GO:0006338; P:chromatin remodeling
; NAS:UniProtKB; .
GO
GO:0016569; P:covalent chromatin modification
; IEA:UniProtKB-KW; .
GO
GO:0045892; P:negative regulation of transcription
; DNA-templated; IDA:UniProtKB
GO
GO:0048511; P:rhythmic process
; IEA:UniProtKB-KW; .
GO
GO:0006351; P:transcription
; DNA-templated; IEA:UniProtKB-KW
InterPro
IPR000953; Chromo/chromo_shadow_dom
; .
InterPro
IPR017984; Chromo_dom_subgr
; .
InterPro
IPR023780; Chromo_domain
; .
InterPro
IPR008251; Chromo_shadow_dom
; .
InterPro
IPR016197; Chromodomain-like
; .
InterPro
IPR023779; Chromodomain_CS
; .
Pfam
PF00385; Chromo
; 1; .
Pfam
PF01393; Chromo_shadow
; 1; .
PRINTS
PR00504; CHROMODOMAIN
; .
SMART
SM00298; CHROMO
; 2; .
SMART
SM00300; ChSh
; 1; .
SUPFAM
SSF54160; SSF54160
; 2; .
PROSITE
PS00598; CHROMO_1
; 1; .
PROSITE
PS50013; CHROMO_2
; 2; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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